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Profs. Jason Hall-Spencer and Kazuo Inaba published a collaborative research with Chinese Academy of Fishery Sciences, Xiamen University, Monash University and University of Tasmania on the flagellar motility of unicellular green algae in the journal ’Nature Climate Change’.
Associate Prof. Shunsuke Yaguchi, Post-doctoral fellow Junko Yaguchi, and Ph.D. Student Haruka Suzuki in Shimoda Marine Research Center, University of Tsukuba, have created a genome edited sea urchin strain. Using CRISPR-Cas9 system, they have knockout Pks1 gene, which is responsible for pigment synthesis, and have created albino sea urchins. This work was done in collaboration with researchers of National Institute of Genetics, Ochanomizu University, and Hiroshima University. This result is published in Current Biology.
Professors Kazuo Inaba and Jason Hall-Spencer (University of Plymouth) published the first English-language book 'Japanese Marine Life - A Practical Training Guide in Marine Biology’ from Springer Nature. This book is aimed to be a marine biology textbook for increasing foreign students to Japan, as well as introducing Japanese marine fauna and flora to students and researchers in marine biology. Teaching staff of SMRC, as well as marine biologists in Japanese marine stations, participate in this book as authors.
In collaboration with researchers from the Universities of Palermo (Italy) and Plymouth (UK), Assist. Prof Sylvain Agostini, Assist. Prof. Ben Harvey, Assist. Prof. Shigeki Wada and Prof. Kazuo Inaba, recently published their research in the journal "Science of the Total Environment" on the effect of ocean acidification on corals and macroalgae and the cascading effects on the fish communities. The surveys conducted at the CO2 seep off the shore of Shikine Island, showed that increasing levels of CO2 lead to the loss of corals and macroalgae and an increase in turf algae. This shift from complex reefs to habitats dominated by opportunistic low-profile algae led to a 45% decrease of fish diversity, with a loss of coral-associated species and a rearrangement of feeding behaviour.
Prof. Yasunori Sasakura, his colleagues and collaborators demonstrate that neurotransmitter GABA is a key regulator of metamorphosis in the ascidian Ciona. This study was on-line published in the journal Current Biology on March 26, 2020.
Kei Jokura (a PhD student, Inaba lab, SMRC) was awarded the Presidents Award for his academic and research performance during his PhD course.
Prof. Jason Hall-Spencer gave an evening lecture on the ocean acidification at the Linnean Society of London, a historical well-renowned society in the world. The Society once had a fellow Charles Darwin and the first female President Irene Manton.
Kei Jokura, a PhD student, Dr. Daisuke Shibata, former Postdoctoral Fellow, Assistant Prof. Kogiku Shiba and Prof. Kazuo Inaba at the Shimoda Marine Research Center, University of Tsukuba found a novel protein involved in the formation of the comb plate in ctenophore. This work was carried out in collaboration with a research group at the National Institute for Basic Biology. These results were published online in Current Biology.
Junko Yaguchi (JSPS Research Fellowship for Young Scientists) was awarded Encouragement Award for Women Scientists (OM Award) from the Zoological Society of Japan for her work on ‘The relationship between the brain and enteric nervous system and its evolution’.
At the 90th Annual Meeting of the Zoological Society of Japan, held in Osaka, Japan, Takeo Horie (Assistant Professor) was awarded the Young Scientist Initiative Award from the Zoological Society of Japan for his work on 'Research on the neural circuit development and function of ascidian larvae'.
Dr. Mami Nomura (Former Postdoctoral Fellow), Assistant Prof. Kogiku Shiba and Prof. Kazuo Inaba at Shimoda Marine Research Center, University of Tsukuba discovered a cryptic cyanobacterial lineage with a worldwide distribution by single-cell genomics in collaboration with Assistant Prof. Takuro Nakayama and his research group at Tohoku university. These results were published online in Proceedings of the National Academy of Sciences of the United States of America (PNAS).
Assistant Prof. Kogiku Shiba and Prof. Kazuo Inaba at Shimoda Marine Research Center, University of Tsukuba revealed that an axonemal protein, calaxin is involved with ciliopathy in collaboration with research group at National Center for Child Health and Development, Meiji University, Osaka University, The University of Tokyo, Aichi University of Education and National Institute for Basic Biology. These results were published online in Communications Biology.
An international research group including associate professor Hiroaki Nakano at Shimoda Marine Research Center, University of Tsukuba, has shown that the Xenacoelomorpha, composed of marine invertebrate worms Acoelmorpha and Xenoturbella, is a sister group to the Ambulacraria (echinoderms and hemichordates). This result is now available online at Current Biology.
Prof. Jason Hall-Spencer and Assistant Prof. Ben Harvey at the Shimoda Marine Research Center, University of Tsukuba, revealed that ocean acidification could have broad reaching effects on ecosystems and the services they provide. Their new study provides a synthesis of the likely effects of ocean acidification on ecosystem properties, functions and services and is based on laboratory experiments and observations along natural gradients in CO2.
Morihiko Tomatsuri, a graduate student at the Center, was awarded the Best Poster’s Award at the 66 Annual Meeting of the Ecological Society of Japan. His poster was entitled 'The effect of ocean acidification on hermit crab communities'
Masashi Asai, a graduate student at the Center, was awarded the Best Poster Award at the The 71st Annual Meeting of the Zoological Society of Japan Kanto Branch. His poster was entitled 'Morphological observations and phylogenetic analysis of Acoelomorpha collected at Shimoda'
Assistant Prof. Ben Harvey at the Shimoda Marine Research Center, University of Tsukuba, along with co-authors, revealed that climate change will continue to increase the frequency of marine heatwaves and the associated impacts on marine biology could have broad reaching effects on ecosystems and the services they provide. This results is now online at Nature Climate Change
Associate Prof. Shunsuke Yaguchi and JSPS Post-doctoral fellow Junko Yaguchi in Shimoda Marine Research Center, Universtiy of Tsukuba, revealed that the pylorus of sea urchin larvae is regulated by nitric oxide released from the endoderm-derived neuron-like cells. This results is now online in Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Kogiku Shiba (Assistant Professor) was awarded the Young Scientist Initiative Award from the Zoological Society of Japan for her work on ‘Elucidating the mechanism of flagellar and ciliary movement using a novel method of visualization and imaging'.
Kei Jokura, a PhD student in Inaba lab. at Shimoda Marine Research Center, was awarded the Student Presentation Awards for his presentation in The 56th annual meeting of the Biophysical Society of Japan. The title of his presentation was "Identification of a novel protein CTENO64 in giant compound cilia in the ctenophore and its role in the coordinated ciliary movement".
Research group of assistant Prof. Takeo Horie and Prof/Director Yasunori Sasakura, in collaboration with research group at Princeton University, University of Hyogo, Konan University, Okinawa Institute of of Science and Technology Graduate School, reported identification of regulatory cocktail for dopaminergic neurons differentiations in ascidians. These results were published in Genes and Development.
Research group of assistant Prof. Takeo Horie, in collaboration with research group at Princeton University,
proposed a shared evolutionary origins of vertebrate neural crest and cranial placodes.
These results were published in Nature.
The research team composed from Dr Agostini, Dr Harvey, Dr Wada, Dr Kon and Dr
Inaba from the Shimoda Marine Research Center in collaboration with Dr Hall-
Spencer from Plymouth University and Dr Milazzo from the University of
Palermo, reported their finding from the studies at the Shikine Island CO2
seep in a paper published in Scientific Reports on July 27th 2018. They show
that the increase in CO2 over the last century has already changed the
structure of marine ecosystems and that if CO2 keeps increasing, this will
lead to drastic simplification of the ecosystems and a loss in biodiversity.
Associate Prof. Shunsuke Yaguchi, Shimoda Marine Research Center, University of Tsukuba, in collaboration with researchers at National Institute of Genetics, Hiroshima University, and Ochanomizu University read the draft genome of a sea urchin, Hemicentrotus pulcherrimus, and made a database HpBase (http://cell-innovation.nig.ac.jp/Hpul/). This result was
published in Development Growth and Differentiation
(https://onlinelibrary.wiley.com/doi/full/10.1111/dgd.12429).
Associate Prof. Hiroaki Nakano and Dr. Hideyuki Miyazawa at Shimoda Marine Research Center, University of Tsukuba, in collaboration with researchers at National Institute of Genetics, Hokkaido University, Okinawa Institute of Science and Technology Graduate University and The University of Tokyo, succeeded in the collection of Xenoturbella for the first time in the waters near Japan and revealed that they are a new species. These results were published in BMC Evolutionary Biology.
Open Laboratory and Public Lectures were held at Shimoda Marine Research Center.
Bilateral Joint Research Seminar between Shimoda Marine Research Center and Laboratoire de Biologie du Développement de Villefranche-sur-mer, CNRS Sorbonne Université, France was held at Shimoda Marine Research Center.
Dr. Katsutoshi Mizuno, Assistant Prof. Kogiku Shiba, Dr. Daisuke Shibata, and Prof. Kazuo Inaba at Shimoda Marine Research Center, University of Tsukuba revealed that an axonemal protein, calaxin is essential for coordinated movement of sea urchin embyos in collaboration with Associate Prof. Shunsuke Yaguchi and Dr. Junko Yaguchi at Shimoda Marine Research Center and research group at the Villefranche-sur-mer Developmental Biology Laboratory, France. These results were published online in Scientific Reports.
The Global Ocean Science Report (GOSR) has been published from UNESCO-IOC (Intergovernmental Oceanographic Commission), providing information on the science capacity in the world and addressing the global challenges towards the attainment of SDG Target 14. Director and Professor Kazuo Inaba has contributed to GOSR as an author and a member of Editorial Board.
Assistant Prof. Kogiku Shiba and Prof. Kazuo Inaba revealed an inverse relationship of a regulatory mechanism in flagellar motility between animal and plant. They analyzed the flagellar Ca2+-response of sperm flagella of the sea urchin Anthocidaris crassispinathe and prasinophyte Pterosperma cristatum. Their results support the idea previously proposed that the difference in flagellar response to Ca2+ attributes to the evolutional innovation of calcium sensors of outer arm dynein in opisthokont or bikont lineage.
Uchu Yamakawa, an undergraduate student at the Center, was awarded the School of Life and Environmental Sciences Provost’s Award for his outstanding achievements during his undergraduate research.
Kogiku Shiba (Assistant Professor) was awarded the "Yasui Kono" Award for Women Scientists from Ochanomizu University for her works on `The mechanism of flagellar and ciliary movement'. Yasui Kono (1880-1971) was a Japanese biologist and the first Japanese woman to receive a doctoral degree in science.
16 staff and students participated in the Basic Lifesaving Course held at the Shimoda Fire Department.
Tsunami Emergency Drill was carried out at the Center. All participants were able to evacuate to the designated meeting point, situated 39 meters above sea level, within 5 minutes of the tsunami warning.
Research group of professor Yasunori Sasakura, in collaboration with research groups at University of Tokyo, Tokyo Metropolitan University, Hiroshima University and Kochi University, proposed a new hypothesis about the evolutionary process of how the ascidian cellulose synthase became to be specifically expressed in the epidermis.
Dr. Kai Chen from Lewis-Sigler Institute for Integrative Genomics, Princeton University,
give a talk about the molecular mechanisms of zygotic genome activation in fly and ascidian embryos.
Morihiko Tomatsuri, a graduate student at the Center, was awarded the Best Poster’s Award at the 2016 Chubu Branch Meeting of the Ecological Society of Japan. His poster was entitled 'The Effect of Ocean Acidification to Hermit crabs in Intertidal Rocky Shores'
Professor Robert Burke from University of Victoria, Canada, gave a talk about the molecular mechanisms of neurogenesis during the sea urchin development.
Kogiku Shiba (Assistant Professor) was awarded the Morita Encouragement Award for Young Women Scientists from Japanese Association of University Women (JAUW) for her work on `Molecular Cell Biology Research on the Flagellar and ciliary movement'.
Developmental biology lab (Junko Yaguchi, JSPS post-doctoral fellow, Noriyo Takeda, post-doctoral fellow and Shunsuke Yaguchi, Associate Professor) revealed the molecular mechanism that exerts a default neural fate at the precise small location during embryogenesis along with the coordination of different body axes formation. The results were published in PLoS Genetics. This study was collaborated with Kazuo Inaba (Director, Professor) in Shimoda Marine Research Center, University of Tsukuba.
Yosuke Ogura and Yasunori Sasakura recently published a new manuscript that discovered a new mechanism of cell cycle compensation during neural tube closure in Ciona.
Opening Ceremony of the SMRC "Shikine-Island Marine Station" was held on Shikine-Island.
Morihiko Tomatsuri, a graduate student at the Center, was awarded the Graduate School of Life and Environmental Sciences Provost's Award for his outstanding achievements during his graduate research.
Open Laboratory and Public Lectures were held at Shimoda Marine Research Center.



Kazuo Inaba (Professor, Director) and Shigeki Wada (Assistant Professor) will give a talk at the public symposium 'Conservation of Marine Biodiversity under Global Environmental Change', November 8th, held by the Certificate Programme on Nature Conservation, University of Tsukuba.
Research group of Kogiku Shiba (Assistant Professor) and Kazuo Inaba (Professor, Director), in collaboration with Osaka University, discovered that the sperm-specific isoform of an enzyme called calcineurin is essential for normal sperm motility and male fertility. These results were published online in Science on October 1st, 2015.
At the 86th Annual Meeting of the Zoological Society of Japan, held in Niigata, Japan, Hiroaki Nakano (Associate Professor) was awarded the Young Scientist Initiative Award from the Zoological Society of Japan for his work on 'Evolutionary developmental research on the life histories of non-model marine animals'.
Morihiko Tomatsuri, a graduate student at the Center, was awarded the Best Poster’s Award at the 8th Japan-China-Korea Graduate Student Forum. His poster was entitled 'A predator is also an architect! Reforming oyster into suitable habitat.’
Shizuoka Governor Heita Kawakatsu visited our Center to acknowledge our scientific and educational activities. Director Kazuo Inaba gave a tour around the Center, including the laboratories, tsunami evacuation route, and the outdoor fish tanks.
Two junior high school students visited our Center as a workplace experience program. They experienced the daily work of researchers and technicians for two days, June 11th and 12th.
Research group of Hiroaki Nakano (Associate Professor) published their research on the discovery of about 50 new species around Sagami Bay.
Nicholas Treen, a graduate student at the Center, was awarded the Graduate School of Life and Environmental Sciences Doctoral Program in Biological Sciences Chair's Award for his outstanding achievements during his graduate research.
Masafumi Kodama, an undergraduate student at the Center, was awarded the College of Biological Sciences Dean’s Award for his outstanding achievements during his undergraduate research.
Morihiko Tomatsuri, a graduate student at the Center, was awarded the Best Poster’s Award at the 2014 Chubu Branch Meeting of the Ecological Society of Japan. His poster was entitled 'Stability mechanisms of food web structure: effects of prey preference of carnivorous gastropod Thais (Reishia) clavigera.'
A course for kids, ‘Let’s examine the shark body’, taught by Hiroaki Nakano (Assistant Professor) and organized by the Denno Shimoda Kurofune School was held at the Center. 
Dr. Osamu Shimomura, who was awarded the 2008 Nobel Prize in Chemistry for his work on the discovery and development of the green fluorescent protein GFP, visited our Center. He toured the Center and participated in plankton collections aboard the research vessel ‘Tsukuba II’.
Toshihiko Sato (Technical Staff) received a 'Certificate of Appreciation' from the Zoological Society of Japan for his many years of contributions in supporting research and education on marine biology at Shimoda Marine Research Center.
Kogiku Shiba (Assistant Professor) was awarded the Best Presentation Award at the12th International Symposium on Spermatology, held in New Castle, Australia.
Hiroaki Nakano (Assistant Professor) succeeded in collecting the simplest free-living animal, the placozoans, across Japan.
Hiroaki Nakano (Assistant Professor) was awarded the Young Staffs' Special Incentive Award, from the President of University of Tsukuba
Research group of Yasunori Sasakura (Professor) developed a new method ‘MASK’ for investigating gene functions in the ascidian eggs.
Research group of Kazuo Inaba (Professor) and Kogiku Shiba (Assistant Professor) published their research on the sperm swimming behavior in a marine gastropod.
Hiroaki Nakano (Assistant Professor) was awarded the Young Scientists' Prize of the Commendation for Science and Technology by the Minister of Education, Culture, Sports, and Technology (MEXT) for his 'Research on the Evolution of Development Using Non-Model Marine Animals'.
Morihiko Tomatsuri, an undergraduate student at the Center, was awarded the School of Life and Environmental Sciences Provost’s Award for his outstanding achievements during his undergraduate research.
Concurrent with the University of Tsukuba Disaster Drill at University of Tsukuba main campus, Tsunami Emergency Drill was carried out at the Center. All 71 participants (46 center staff and students, 25 renovation construction workers), were all able to evacuate to the designated meeting point, situated 39 meters above sea level, within 5 minutes of the tsunami warning.
An article on Hiroaki Nakano (Assistant Professor) appears in the 'University of Tsukuba by AERA MOOK'.
Hiroaki Nakano (Assistant Professor) was awarded the Young Scientist Initiative Award from the Society of Evolutionary Studies, Japan.
Sylvain Agostini (Assistant Professor) was awarded the Best Paper Award of the year 2012 in the journal Coral Reefs published by the International Coral Reef Society (ISRS).
Shimoda City Tsunami Emergency Drill was carried out with about 21 participants, including center staff, researchers, students, and neighbors. Participants were all able to evacuate to the designated meeting point within 9 minutes.
Assistant professor Hiroaki Nakano and his collaborators have succeeded in observing the development of Xenoturbella for the first time since the animal was first discovered more than 130 years ago. These results were published online in Nature Communications on February 26th, 2013.
The 2nd JAMBIO forum was held on January 21st at Shimoda Marine Research Center with participants from Sweden, Hawaii, and many Japanese marine stations and universities.
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