トップページ > 原著論文

原著論文 / 学会発表



Taniguchi S, Nakayama S, Iguchi R, Sasakura Y, Satake H, Wada S, Suzuki N, Ogasawara M, Sekiguchi T.
Distribution of cionin, a cholecystokinin/gastrin family peptide, and its receptor in the central nervous system of Ciona intestinalis type A.
Sci Rep. 2024 Mar 15;14(1):6277. doi: 10.1038/s41598-024-55908-7.
PMID: 38491056

Krasovec G, Renaud C, Queinnec E, Sasakura Y, Chambon JP.
Extrinsic apoptosis participates to tail regression during the metamorphosis of the chordate Ciona.
Sci Rep. 2024 Mar 8;14(1):5729. doi: 10.1038/s41598-023-48411-y.
PMID: 38459045

Satake H, Sasakura Y.
The neuroendocrine system of Ciona intestinalis Type A, a deuterostome invertebrate and the closest relative of vertebrates.
Mol Cell Endocrinol. 2023 Dec 16;582:112122. doi: 10.1016/j.mce.2023.112122.
PMID: 38109989

Kijima T, Kurokawa D, Sasakura Y, Ogasawara M, Aratake S, Yoshida K, Yoshida M.
CatSper mediates not only chemotactic behavior but also the motility of ascidian sperm.
Front Cell Dev Biol. 2023 Nov 2;11:1136537. doi: 10.3389/fcell.2023.1136537.
PMID: 38020915

Totsuka NM, Kuwana S, Sawai S, Oka K, Sasakura Y, Hotta K
Distribution changes of non-self-test cells and self-tunic cells surrounding the outer body during Ciona metamorphosis.
Dev Dyn. 2023 Nov;252(11):1363-1374. doi: 10.1002/dvdy.636.
PMID: 37341471

Iguchi R, Usui K, Nakayama S, Sasakura Y, Sekiguchi T, Ogasawara M
Multi-regional expression of pancreas-related digestive enzyme genes in the intestinal chamber of the ascidian Ciona intestinalis type A.
Cell Tissue Res. 2023 Oct 25. doi: 10.1007/s00441-023-03839-6.
PMID: 37878073

Sakai T, Yamamoto T, Watanabe T, Hozumi A, Shiraishi A, Osugi T, Matsubara S, Kawada T, Sasakura Y, Takahashi T, Satake H
Characterization of a novel species-specific 51-amino acid peptide, PEP51, as a caspase-3/7 activator in ovarian follicles of the ascidian, Ciona intestinalis Type A.
Front Endocrinol (Lausanne). 2023 Sep 29;14:1260600. doi: 10.3389/fendo.2023.1260600.
PMID: 37842312

Iguchi R, Nakayama S, Sasakura Y, Sekiguchi T, Ogasawara M
Repetitive and zonal expression profiles of absorption-related genes in the gastrointestinal tract of ascidian Ciona intestinalis type A.
Cell Tissue Res. 2023 Sep 6. doi: 10.1007/s00441-023-03828-9.
PMID: 37670165

Treen N, Konishi S, Nishida H, Onuma TA, Sasakura Y
Zic-r.b controls cell numbers in Ciona embryos by activating CDKN1B.
Dev Biol. 2023 Mar 23;498:26-34. doi: 10.1016/j.ydbio.2023.03.005.
PMID: 36965841

Sasakura Y, Horie T
Improved Genome Editing in the Ascidian Ciona with CRISPR/Cas9 and TALEN.
Methods Mol Biol. 2023;2637:375-388. doi: 10.1007/978-1-0716-3016-7_28.
PMID: 36773161


Yamakawa S, Hayashi Y, Kako K, Sasakura Y, Morino Y, Wada H
Mechanism underlying retinoic acid-dependent metamorphosis in the starfish.
Dev Biol. 2022 Dec;492:119-125. doi: 10.1016/j.ydbio.2022.10.002.
PMID: 36240875

Sakamoto A, Hozumi A, Shiraishi A, Satake H, Horie T, Sasakura Y
The TRP channel PKD2 is involved in sensing the mechanical stimulus of adhesion for initiating metamorphosis in the chordate Ciona.
Dev Growth Differ. 2022 Jul 30. doi: 10.1111/dgd.12801.
PMID: 36053743

Yamagishi M, Huang T, Hozumi A, Onuma TA, Sasakura Y, Ogasawara M
Differentiation of endostyle cells by Nkx2-1 and FoxE in the ascidian Ciona intestinalis type A: insights into shared gene regulation in glandular- and thyroid-equivalent elements of the chordate endostyle.
Cell Tissue Res. 2022 Sep 1. doi: 10.1007/s00441-022-03679-w.
PMID: 36048302

Khalturin K, Shunatova N, Shchenkov S, Sasakura Y, Kawamitsu M, Satoh N
Polyzoa is back: The effect of complete gene sets on the placement of Ectoprocta and Entoprocta.
Sci Adv. 2022 Jul 8(26):eabo4400. DOI: 10.1126/sciadv.abo4400
PMID: 35776797


Krasovec G, Hozumi A, Yoshida T, Obita T, Hamada M, Shiraishi A, Satake H, Horie T, Mori H, Sasakura Y
d-Serine controls epidermal vesicle release via NMDA receptor, allowing tissue migration during the metamorphosis of the chordate Ciona.
Sci Adv. 2022 Mar 11;8(10):eabn3264. doi: 10.1126/sciadv.abn3264
PMID: 35275721

Chacha PP, Horie R, Kusakabe TG, Sasakura Y, Singh M, Horie T, Levine M
Neuronal identities derived by misexpression of the POU IV sensory determinant in a protovertebrate.
Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2118817119. doi: 10.1073/pnas.2118817119.
PMID: 35042818

Yamazaki A, Yamakawa S, Morino Y, Sasakura Y, Wada H.
Gene regulation of adult skeletogenesis in starfish and modifications during gene network co-option.
Sci Rep. 2021. 11(1):20111. doi: 10.1038/s41598-021-99521-4.
PMID: 34635691

Sasakura Y, Harvey BP.
Institute Profile: Shimoda Marine Research Center, University of Tsukuba.
Limnol Oceanogr Bull. 2021. 30(3):116-118. doi: 10.1002/lob.10457.

Onuma T, Nakanishi R, Sasakura Y, Ogasawara M
Nkx2-1 and FoxE regionalize glandular (mucus-producing) and thyroid-equivalent traits in the endostyle of the chordate Oikopleura dioica.
Dev Biol. 2021 Jun 6;477:219-231. doi: 10.1016/j.ydbio.2021.05.021.
PMID: 34107272

Kawada T, Shiraishi A, Matsubara S, Hozumi A, Horie T, Sasakura Y, Satake H.
Vasopressin Promoter Transgenic and Vasopressin Gene-Edited Ascidian, Ciona intestinalis Type A (Ciona robusta): Innervation, Gene Expression Profiles, and Phenotypes.
Front Endocrinol (Lausanne). 2021 May 6;12:668564. doi: 10.3389/fendo.2021.668564. eCollection 2021.
PMID: 34025581


Yamaji S, Hozumi A, Matsunobu S, Sasakura Y.
Orchestration of the distinct morphogenetic movements in different tissues drives tail regression during ascidian metamorphosis.
Dev Biol. 2020 Sep 1;465(1):66-78. doi: 10.1016/j.ydbio.2020.07.009.
PMID: 32697971

Hozumi A, Matsunobu S, Mita K, Treen N, Sugihara T, Horie T, Sakuma T, Yamamoto T, Shiraishi A, Hamada M, Satoh N, Sakurai K, Satake H, Sasakura Y.
GABA-Induced GnRH Release Triggers Chordate Metamorphosis.
Curr Biol. 2020 Apr 20;30(8):1555-1561.e4. doi: 10.1016/j.cub.2020.02.003.
PMID: 32220316


Sawada H, Yamamoto K, Yamaguchi A, Yamada L, Higuchi A, Nukaya H, Fukuoka M, Sakuma T, Yamamoto T, Sasakura Y, Shirae-Kurabayashi M.
Three multi-allelic gene pairs are responsible for self-sterility in the ascidian Ciona intestinalis.
Sci Rep. 2020 Feb 13;10(1):2514. doi: 10.1038/s41598-020-59147-4.
PMID: 32054881

Osugi T, Sasakura Y, Satake H.
The ventral peptidergic system of the adult ascidian Ciona robusta (Ciona intestinalis Type A) insights from a transgenic animal model.
Sci Rep. 2020 Feb 5;10(1):1892. doi: 10.1038/s41598-020-58884-w.
PMID: 32024913

Tajima Y, Hozumi A, Yoshida K, Treen N, Sakuma T, Yamamoto T, Sasakura Y.
Hox13 is essential for formation of a sensory organ at the terminal end of the sperm duct in Ciona.
Dev Biol. 2019 Feb 1;458(1):120-131. doi: 10.1016/j.ydbio.2019.10.028.
PMID: 31682808


Yasunori Sasakura.
Cellulose production and the evolution of the sessile lifestyle in ascidians
2018 Volume 35 Issue 2 Pages 21-29 .doi:https://doi.org/10.4282/sosj.35.21

Satoh T, Iitsuka T, Shiraishi A, Hozumi A, Satake H, Sasakura Y.
piRNA-like small RNAs are responsible for the maternal-specific knockdown in the ascidian Ciona intestinalis Type A.
Sci Rep. 2018 Apr 12;8(1):5869. doi: 10.1038/s41598-018-24319-w.
PMID: 29651003

Horie T, Horie R, Chen K, Cao C, Nakagawa M, Kusakabe TG, Satoh N, Sasakura Y, Levine M.
Regulatory cocktail for dopaminergic neurons in a protovertebrate identified by whole-embryo single-cell transcriptomics.
Genes Dev. 2018 Oct 1;32(19-20):1297-1302. doi: 10.1101/gad.317669.118. Epub 2018 Sep 18.
PMID: 30228204

Sasakura Y, Hozumi A.
Formation of adult organs through metamorphosis in ascidians.
Wiley Interdiscip Rev Dev Biol. 2018 Mar;7(2). doi: 10.1002/wdev.304.
PMID: 29105358

Sasakura Y.
Germline Transgenesis in Ciona.
Adv Exp Med Biol. 2018;1029:109-119. doi: 10.1007/978-981-10-7545-2_10.
PMID: 29542084

Sasakura Y.
The Enhancer Trap in Ciona.
Adv Exp Med Biol. 2018;1029:121-129. doi: 10.1007/978-981-10-7545-2_11.
PMID: 29542085


Ogura Y, Sasakura Y.
Emerging mechanisms regulating mitotic synchrony during animal embryogenesis.
Dev Growth Differ. 2017 Aug 22. doi: 10.1111/dgd.12391. [Epub ahead of print] Review.

Osugi T, Sasakura Y, Satake H.
The nervous system of the adult ascidian Ciona intestinalis Type A (Ciona robusta): Insights from transgenic animal models.
PLoS One. 2017 Jun 26;12(6):e0180227. doi: 10.1371/journal.pone.0180227. eCollection 2017.

Sasakura Y, Yoshida K, Treen N.
Genome Editing of the Ascidian Ciona intestinalis with TALE Nuclease.
Methods Mol Biol. 2017;1630:235-245. doi: 10.1007/978-1-4939-7128-2_19.

Yoshida K, Nakahata A, Treen N, Sakuma T, Yamamoto T, Sasakura Y.
Hox-mediated endodermal identity patterns pharyngeal muscle formation in the chordate pharynx.
Development. 2017 May 1;144(9):1629-1634. doi: 10.1242/dev.144436. Epub 2017 Mar 13.


Yoshida K, Hozumi A, Treen N, Sakuma T, Yamamoto T, Shirae-Kurabayashi M, Sasakura Y.
Germ cell regeneration-mediated, enhanced mutagenesis in the ascidian Ciona intestinalis reveals flexible germ cell formation from different somatic cells.
Dev Biol 2017 Mar 15;423(2):111-125. doi: 10.1016/j.ydbio.2017.01.022. Epub 2017 Feb 1.

Ogura Y, Sasakura Y.
Switching the rate and pattern of cell division for neural tube closure.
Neurogenesis (Austin). 2016 Sep 30;3(1):e1235938. eCollection 2016.

Sasakura Y, Ogura Y, Treen N, Yokomori R, Park SJ, Nakai K, Saiga H, Sakuma T, Yamamoto T, Fujiwara S, Yoshida K.
Transcriptional regulation of a horizontally transferred gene from bacterium to chordate.
Proc Biol Sci. 2016 Dec 28;283(1845). pii: 20161712. doi: 10.1098/rspb.2016.1712.

Ogura Yosuke, Sasakura Yasunori
Cell-cycle compensation coupled with developmental patterning
Cell Cycle. 2016 Oct 17;15(20):2685-6. doi: 10.1080/15384101.2016.1204859.

Ogura Yosuke, Sasakura Yasunori
Developmental Control of Cell-Cycle Compensation Provides a Switch for Patterned Mitosis at the Onset of Chordate Neurulation
Dev Cell. 2016 Apr 18;37(2):148-61. doi: 10.1016/j.devcel.2016.03.013.
→ Developmental Cell 誌電子版にて、筆頭著者である小椋さんのインタビュー記事が掲載されました。


Narudo Kawai, Yosuke Ogura, Tetsuro Ikuta, Hidetoshi Saiga, Mayuko Hamada, Tetsushi Sakuma, Takashi Yamamoto, Nori Satoh, Yasunori Sasakura
Hox10-regulated endodermal cell migration is essential for development of the ascidian intestine
Developmental Biology403(2015)43-56

Akiko Hozumi, Takeo Horie, and Yasunori Sasakura
Neuronal map reveals the highly regionalized pattern of the juvenile central nervous system of the ascidian Ciona intestinalis
Developmental Dynamics DOI 10.1002/dvdy.24317

Shohei Matsunobu, Yasunori Sasakura
Time course for tail regression during metamorphosis of the ascidian Ciona intestinalis
Developmental Biology405(2015)71-81

N Treen, Y Sasakura
Genome Editing in Ascidians
Targeted Genome Editing Using Site-Specific Nucleases, 2015 - Springer

Karaiskou A, Swalla BJ, Sasakura Y, Chambon JP.
Metamorphosis in solitary ascidians.
Genesis. 2015 Jan;53(1):34-47.

Stolfi A, Sasakura Y, Chalopin D, Satou Y, Christiaen L, Dantec C, Endo T, Naville M, Nishida H, Swalla BJ, Volff JN, Voskoboynik A, Dauga D, Lemaire P.
Guidelines for the nomenclature of genetic elements in tunicate genomes.
Genesis. 2015 Jan;53(1):1-14.

Satou Y, Hirayama K, Mita K, Fujie M, Chiba S, Yoshida R, Endo T, Sasakura Y, Inaba K, Satoh N.
Sustained heterozygosity across a self-incompatibility locus in an inbred ascidian..
Mol Biol Evol. 2015 Jan;32(1):81-90.


Kamiya C, Ohta N, Ogura Y, Yoshida K, Horie T, Kusakabe TG, Satake H, Sasakura Y.
Nonreproductive role of gonadotropin-releasing hormone in the control of ascidian metamorphosis.
Dev Dyn. 2014 Dec;243(12):1524-35. doi: 10.1002/dvdy.24176. Epub 2014 Aug 22.

Iitsuka T, Mita K, Hozumi A, Hamada M, Satoh N, Sasakura Y.
Transposon-mediated targeted and specific knockdown of maternally expressed transcripts in the ascidian Ciona intestinalis.
Sci Rep. 2014 May 23;4:5050. doi: 10.1038/srep05050.

Sasaki H, Yoshida K, Hozumi A, Sasakura Y.
CRISPR/Cas9-mediated gene knockout in the ascidian Ciona intestinalis.
Dev Growth Differ. 2014 Sep;56(7):499-510.

Iitsuka T, Mita K, Hozumi A, Hamada M, Satoh N, Sasakura Y.
Transposon-mediated targeted and specific knockdown of maternally expressed transcripts in the ascidian Ciona intestinalis.
Sci Rep. 2014 May 23;4:5050. doi: 10.1038/srep05050.

Yoshida K, Treen N, Hozumi A, Sakuma T, Yamamoto T, Sasakura Y.
Germ cell mutations of the ascidian Ciona intestinalis with TALE nucleases.
Genesis. 2014 May;52(5):431-9. doi: 10.1002/dvg.22770. Epub 2014 Mar 19.

Yasunori Sasakura
Germline transformation in the ascidian Ciona intestinalis.
In: Sexual reproduction in animals and plants (eds H. Sawada, N. Inoue, M.Iwano).
Springer (2014).

Nicholas Treen, 吉田慶太、佐々木陽香、笹倉靖徳
実験医学別冊 今すぐ始めるゲノム編集(山本卓編)pp161-168, 2014 Mar.

Treen N, Yoshida K, Sakuma T, Sasaki H, Kawai N, Yamamoto T, Sasakura Y.
Tissue-specific and ubiquitous gene knockouts by TALEN electroporation provide new approaches to investigating gene function in Ciona.
Development. 2014 Jan;141(2):481-7

月刊むし 2014年11月号(通巻525号) p61

月刊むし 2014年10月号(通巻524号) p54


Miho M Suzuki, Akiko Yoshinari, Madoka Obara, Shohei Takuno, Shuji Shigenobu, Yasunori Sasakura, Alastair R. W. Kerr, Shaun Webb, Adrian Bird and Atsuo Nakayama
Identical sets of methylated and nonmethylated genes in Ciona intestinalis sperm and muscle cells.
Epigenetics Chromatin. 2013 Nov 11;6(1):38.

Nakazawa K, Yamazawa T, Moriyama Y, Ogura Y, Kawai N, Sasakura Y, Saiga H.
Formation of the digestive tract in Ciona intestinalis includes two distinct morphogenic processes between its anterior and posterior parts.
Dev Dyn. 2013 Oct;242(10):1172-83.

Ogura Y, Sasakura Y.
Ascidians as excellent models for studying cellular events in the chordate body plan.
Biol Bull. 2013 Aug;224(3):227-36.

河合成道、Nicholas Treen、佐々木陽香、笹倉靖徳
細胞工学 Vol. 32 No. 5 2013, p553-557

Sakuma T, Hosoi S, Woltjen K, Suzuki K, Kashiwagi K, Wada H, Ochiai H, Miyamoto T, Kawai N, Sasakura Y, Matsuura S, Okada Y, Kawahara A, Hayashi S, Yamamoto T.
Efficient TALEN construction and evaluation methods for human cell and animal applications.
Genes Cells. 2013 Apr;18(4):315-26.

ユビキチンオシレイターによる細胞周期可視化 – 細胞周期を四次元で理解する
実験医学 Vol. 31 No. 2 (増刊)2013, p178 (308)-185 (315)

Hozumi A, Yoshida R, Horie T, Sakuma T, Yamamoto T, Sasakura Y.
Enhancer activity sensitive to the orientation of the gene it regulates in the chordate genome.
Dev Biol. 2013 Mar 1;375(1):79-91.

Hozumi A, Mita K, Miskey C, Mates L, Izsvak Z, Ivics Z, Satake H, Sasakura Y.
Germline transgenesis of the chordate Ciona intestinalis with hyperactive variants of sleeping beauty transposable element.
Developmental Dynamics 2013 Jan;242(1):30-43.


Yasunori Sasakura, Nicolas Sierro, Kenta Nakai, Kazuo Inaba, Takehiro G. Kusakabe
Genome structure, functional genomics, and proteomics in ascidians.
In, Genome Mapping and Genomics in Laboratory Animals (eds, P. Denny and C. Kole, Springer) p87-132.

Mita K, Kawai N, Rueckert S, Sasakura Y
Large-scale infection of the ascidian Ciona intestinalis by the gregarine Lankesteria ascidiae in an inland culture system.
Diseases of Aquatic Organisms 2012 Nov 19;101(3):185-95.

Razy-Krajka F, Brown E, Horie T, Callebert J, Sasakura Y, Joly JS, Kusakabe T, Vernier P.
Monoaminergic modulation of photoreception in ascidian: Evidence for a proto-hypothalamo-retinal territory.
BMC Biol. 2012 May 29;10(1):45.

Kawai N, Ochiai H, Sakuma T, Yamada L, Sawada H, Yamamoto T, Sasakura Y.
Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases.
Dev Growth Differ. 2012 June;54(5):535-45.

Sasakura Y, Kanda M, Ikeda T, Horie T, Kawai N, Ogura Y, Yoshida R, Hozumi A, Satoh N, Fujiwara S.
Retinoic acid-driven Hox1 is required in the epidermis for forming the otic/atrial placodes during ascidian metamorphosis.
Development (2012) May; 139:2156-2160.

Sasakura Y, Mita K, Ogura Y, Horie T.
Ascidians as excellent chordate models for studying the development of the nervous system during embryogenesis and metamorphosis.
Dev Growth Differ. 2012 Apr;54(3):420-37.

Nishitsuji K, Horie T, Ichinose A, Sasakura Y, Yasuo H, Kusakabe TG.
Cell lineage and cis-regulation for a unique GABAergic/glycinergic neuron type in the larval nerve cord of the ascidian Ciona intestinalis.
Dev Growth Differ. 2012 Feb;54(2):177-86.

Yoshida R, Sasakura Y.
Establishment of Enhancer Detection Lines Expressing GFP in the Gut of the Ascidian Ciona intestinalis.
Zoolog Sci. 2012 Jan;29(1):11-20.


実験医学 vol29, No.9 p1423-1426、2011年

Yoshiyama-Yanagawa T, Enya S, Shimada-Niwa Y, Yaguchi S, Haramoto Y, Matsuya T, Shiomi K, Sasakura Y, Takahashi S, Asashima M, Kataoka H, Niwa R.
The conserved Rieske oxygenase DAF-36/Neverland is a novel cholesterol metabolizing enzyme.
J Biol Chem. 2011 Jul 22;286(29):25756-62.

Hamada M, Shimozono N, Ohta N, Satou Y, Horie T, Kawada T, Satake H, Sasakura Y, Satoh N.

Expression of neuropeptide- and hormone-encoding genes in the Ciona intestinalis Larval Brain.
Dev Biol. 2011 Apr 15;352(2):202-14

Ogura Y, Sakaue-Sawano A, Nakagawa M, Satoh N, Miyawaki A, Sasakura Y.
Coordination of mitosis and morphogenesis: role of a prolonged G2 phase during chordate neurulation.
Development (2011) Feb;138(3):577-87.
→ Development誌電子版トップページのFeatured movieに選ばれました。

Horie T, Shinki R, Ogura Y, Kusakabe TG, Satoh N, Sasakura Y.
Ependymal cells of chordate larvae are stem-like cells that form the adult nervous system.>
Nature (2011) Jan 27;469(7331):525-8.
→ 日本経済新聞 1月3日朝刊【ホヤ幼生の中枢神経、成長後も残存 定説覆す】

Endo T, Ueno K, Yonezawa K, Mineta K, Hotta K, Satou Y, Yamada L, Ogasawara M, Takahashi H, Nakajima A, Nakachi M, Nomura M, Yaguchi J, Sasakura Y, Yamasaki C, Sera M, Yoshizawa AC, Imanishi T, Taniguchi H, Inaba K.
CIPRO 2.5: Ciona intestinalis protein database, a unique integrated repository of large-scale omics data, bioinformatic analyses and curated annotation, with user rating and reviewing functionality.
Nucleic Acids Res. 2011 Jan;39(Database issue):D807-14.


Ohta N, Horie T, Satoh N, Sasakura Y.
Transposon-Mediated Enhancer Detection Reveals the Location, Morphology and Development of the Cupular Organs, which are Putative Hydrodynamic Sensors, in the Ascidian Ciona intestinalis.
Zoolog Sci. (2010) Nov;27(11):842-50.

Terakubo HQ, Nakajima Y, Sasakura Y, Horie T, Konno A, Takahashi H, Inaba K, Hotta K, Oka K.
Network structure of projections extending from peripheral neurons in the tunic of ascidian larva.
Dev Dyn. (2010) Aug;239(8):2278-87.

Hozumi A, Kawai N, Yoshida R, Ogura Y, Ohta N, Satake H, Satoh N, Sasakura Y.
Efficient transposition of a single Minos transposon copy in the genome of the ascidian Ciona intestinalis with a transgenic line expressing transposase in eggs.
Dev Dyn. (2010) Apr;239(4):1076-88.

Sasakura Y, Yaguchi J, Yaguchi S, Yajima M.
Excision and Transposition Activity of Tc1/mariner Superfamily Transposons in Sea Urchin Embryos.
Zoolog Sci. (2010) Mar;27(3):256-62.

Horie T, Nakagawa M, Sasakura Y, Kusakabe TG, Tsuda M.
Simple Motor System of the Ascidian Larva: Neuronal Complex Comprising Putative Cholinergic and GABAergic/Glycinergic Neurons.
Zoolog Sci. (2010) Feb;27(2):181-90.

Auger H, Sasakura Y, Joly JS, Jeffery WR.
Regeneration of oral siphon pigment organs in the ascidian Ciona intestinalis.
Dev Biol. (2010) Mar 15;339(2):374-389.

Sasakura Y, Suzuki MM, Hozumi A, Inaba K, Satoh N.
Maternal factor-mediated epigenetic gene silencing in the ascidian Ciona intestinalis.
Mol Genet Genomics. (2010) Jan 283 (1) : 99-110.

Konno A, Kaizu M, Hotta K, Horie T, Sasakura Y, Ikeo K, Inaba K.
Distribution and structural diversity of cilia in tadpole larvae of the
ascidian Ciona intestinalis.
Dev Biol. (2010) Jan 1;337(1):42-62.

月刊むし 2010年10月号(通巻476号) p47


カタユウレイボヤ・ニッポンウミシダ 海産無脊椎動物を代表する研究材料
細胞工学 別冊「バイオリソース& データベース活用術」p177-180、2009年

Yasunori Sasakura, Kazuo Inaba, Nori Satoh, Mariko Kondo, Koji Akasaka
Ciona intestinalis and Oxycomanthus japonicus, representatives of marine invertebrates
Experimental Animals (2009) 58, 459-469

Yasunori Sasakura.
Regulatory Genes in Ancestral Chordates. In: ENCYCLOPEDIA OF LIFE SCIENCES(September 2009).
John Wiley & Sons, Ltd: Chichester http://www.els.net/ [Doi: 10.1002/9780470015902.a0021774]

中川 将司 , 堀江 健生
ホヤ幼生の光受容器 - 脊椎動物の眼との比較 -   → 比較生理生化学会HPで紹介されました!
比較生理生化学( 2009 ) Vol26.No.3, 101-109

堀江 健生 , 笹倉 靖徳
比較生理生化学( 2009 ) Vol26.No.3, 117-120

Horie T, Nakagawa M, Sasakura Y, Kusakabe TG.
Cell type and function of neurons in the ascidian nervous system.
Development Growth & Differentiation 2009 51;207-220.

Dahlberg C, Auger H, Dupont S, Sasakura Y, Thorndyke M, Joly JS.
Refining the Ciona intestinalis model of central nervous system regeneration.
PLoS ONE. (2009);4(2):e4458.

Nakayama-Ishimura A, Chambon JP, Horie T, Satoh N, Sasakura Y.
Delineating metamorphic pathways in the ascidian Ciona intestinalis.
Dev Biol. (2009) Feb 15;326(2):357-67.


Yasunori Sasakura
Transposon-based technologies in the ascidian Ciona intestinalis
Chapter VI in: "DNA transporsable elements research", Edotors: K. Yoshida and M. Aoki, ISBN :978-1-60456-531-7
(2008),Nova Science Publishers, Inc.

NBRP(ナショナルバイオリソースプロジェクト)紹介 カタユウレイボヤ・ニッポンウミシダ ー海産無脊椎動物のリソース展開ー
季刊 Biophilia (2008) Vol.4 No.4

Holland LZ , Albalat R , Azumi K , Benito-Gutierrez E , Blow MJ , Bronner-Fraser M , Brunet F , Butts T , Candiani S , Dishaw LJ , Ferrier DE , Garcia-Fernandez J , Gibson-Brown JJ , Gissi C , Godzik A , Hallbook F , Hirose D , Hosomichi K , Ikuta T , Inoko H , Kasahara M , Kasamatsu J , Kawashima T , Kimura A , Kobayashi M , Kozmik Z , Kubokawa K , Laudet V , Litman GW , McHardy AC , Meulemans D , Nonaka M , Olinski RP , Pancer Z , Pennacchio LA , Pestarino M , Rast JP , Rigoutsos I , Robinson-Rechavi M , Roch G , Saiga H , Sasakura Y , Satake M , Satou Y , Schubert M , Sherwood N , Shiina T , Takatori N , Tello J , Vopalensky P , Wada S , Xu A , Ye Y , Yoshida K , Yoshizaki F , Yu JK , Zhang Q , Zmasek CM , de Jong PJ , Osoegawa K , Putnam NH , Rokhsar DS , Satoh N , Holland PW .
The amphioxus genome illuminates vertebrate origins and cephalochordate biology.
Genome Research. (2008) Jul;18(7):1100-11.

Satou Y , Wada S , Sasakura Y , Satoh N .

Regulatory genes in the ancestral chordate genomes.
Development Genes and Evolution. (2008) Dec;218(11-12):715-21.

Satou Y , Mineta K , Ogasawara M , Sasakura Y , Shoguchi E , Ueno K , Yamada L , Matsumoto J , Wasserscheid J , Dewar K , Wiley GB , Macmil SL , Roe BA , Zeller RW , Hastings KE , Lemaire P , Lindquist E , Endo T , Hotta K , Inaba K .
Improved genome assembly and evidence-based global gene model set for the chordate Ciona intestinalis: new insight into intron and operon populations.
Genome Biology (2008) Oct 14;9(10):R152.

Sardet C , Swalla BJ , Satoh N , Sasakura Y , Branno M , Thompson EM , Levine M , Nishida H .
Euro chordates: Ascidian community swims ahead. The 4th International Tunicate meeting in Villefranche sur Mer.
Developmental Dynamics (2008) Apr;237(4):1207-13.

Sasakura Y, Konno A, Mizuno K, Satoh N, Inaba K.
Enhancer detection in the ascidian Ciona intestinalis with transposase-expressing lines of Minos.
Developmental Dynamics (2008) 237: 39-50 .


Sessile Organisms (2007) 24(2) : 127-131

Sasakura Y, Oogai Y, Matsuoka T, Satoh N, Awazu S.
Transposon mediated transgenesis in a marine invertebrate chordate: Ciona intestinalis.
Genome Biology (2007) ; 8 Suppl 1 : S3 . Review.

Jean-Stephane Joly, Shungo Kano, Terumi Matsuoka, Helene Auger, Satoko Awazu, Laurent Legendre, Yasunori Sasakura.

Culture of Ciona intestinalis in closed systems
Developmental Dynamics (2007) 236: 1832-40.

Francois Prodon. Lixy Yamada, Maki Shirae-Kurabayashi, Yoriko Nakamura, Yasunori Sasakura
Postplasmic/PEM RNAs: a class of localized maternal mRNAs with multiple roles in cell polarity and development in ascidian embryos.
Developmental Dynamics (2007) 236: 1698-715 . Review.

Yasunori Sasakura
Germline transgenesis and insertional mutangenesis in the ascidian Ciona intestinalis
Developmental Dynamics (2007) 236: 1758-67 . Review.

Awazu Satoko, Terumi Matsuoka, Kazuo Inaba, Nori Satoh, Yasunori Sasakura
High Throughput enhancer trap by re-mobilization of transposon Minos in Ciona intestinalis .
Genesis (2007) 45: 307-317.


笹倉 靖徳、稲葉 一男、佐藤 矩行
細胞工学 (2006) 25: 1460-1461


Yasunori Sasakura, Keisuke Nakashima, Satoko Awazu, Terumi Matsuoka, Akie Nakayama, Jun-ichi Azuma, Nori Satoh
Transposon-mediated insertional mutagenesis revealed the functions of animal cellulose synthase in the ascidian Ciona intestinalis .
Proceedings of National Academy of Science USA (2005) 102: 15134-15139. → 新聞等にも紹介されました!!

Akie Nakayama, Nori Satoh, Yasunori Sasakura
Tissue-specific profile of DNA replication in the swimming larvae of Ciona intestinalis .
Zoological Science (2005) 22: 301-309.

Terumi Matsuoka, Satoko Awazu, Eiichi Shoguchi, Nori Satoh, Yasunori Sasakura
Germline transgenesis of the ascidian Ciona intestinalis by electroporation
Genesis (2005) 41:61-72.


Satoko Awazu, Akane Sasaki, Terumi Matsuoka, Nori Satoh, Yasunori Sasakura
An enhancer trap in the ascidian Ciona intestinalis identifies enhancers of its Musashi orthologous gene
Developmental Biology (2004) 275:459-472.

Terumi Matsuoka, Satoko Awazu, Nori Satoh, Yasunori Sasakura
Minos transposon causes germline transgenesis of the ascidian Ciona savignyi .
Development Growth & Differentiation (2004) 46: 249-255.


Yasunori Sasakura, Satoko Awazu, Shota Chiba, Nori Satoh
Germ-line transgenesis of the Tc1/ mariner superfamily transposon Minos in Ciona intestinalis .
Proceedings of National Academy of Science U S A. (2003) 100:7726-7730.

Yasunori Sasakura, Satoko Awazu, Shota Chiba, Shungo Kano, Nori Satoh
Application of Minos , one of the Tc1/ mariner superfamily transposable elements, to ascidian embryos as a tool for insertional mutagenesis.
Gene (2003) 308:11-20.

Yasunori Sasakura, Lixy Yamada, Naohito Takatori, Yutaka Satou, Nori Satoh
A genomewide survey of developmentally relevant genes in Ciona intestinalis . VII. Molecules involved in the regulation of cell polarity and actin dynamics.
Development Genes and Evolution. (2003) 213:273-283.

Yasunori Sasakura , Eiichi Shoguchi, Naohito Takatori, Shuichi Wada, Ian A Meinertzhagen, Yutaka Satou, Nori Satoh
A genomewide survey of developmentally relevant genes in Ciona intestinalis . X. Genes for cell junctions and extracellular matrix.
Development Genes and Evolution. (2003) 213:303-313.

Yutaka Satou, Yasunori Sasakura, Lixy Yamada, Kaoru S. Imai, Nori Satoh, Bernard Degnan
A genomewide survey of developmentally relevant genes in Ciona intestinalis . V. Genes for receptor tyrosine kinase pathway and Notch signaling pathway.
Development Genes and Evolution. (2003) 213:254-263.


Yasunori Sasakura , Kazuhiro W. Makabe
Identification of cis elements which direct the localization of maternal mRNAs to the posterior pole of ascidian embryos.
Developmental Biology. (2002) 250:128-144.

Dehal P, Satou Y, Campbell RK, Chapman J, Degnan B, De Tomaso A, Davidson B, Di Gregorio A, Gelpke M, Goodstein DM, Harafuji N, Hastings KE, Ho I, Hotta K, Huang W, Kawashima T, Lemaire P, Martinez D, Meinertzhagen IA, Necula S, Nonaka M, Putnam N, Rash S, Saiga H, Satake M, Terry A, Yamada L, Wang HG, Awazu S, Azumi K, Boore J, Branno M, Chin-Bow S, DeSantis R, Doyle S, Francino P, Keys DN, Haga S, Hayashi H, Hino K, Imai KS, Inaba K Kano S, Kobayashi K, Kobayashi M, Lee BI, Makabe KW, Manohar C, Matassi G, Medina M, Mochizuki Y, Mount S, Morishita T, Miura S, Nakayama A, Nishizaka S, Nomoto H, Ohta F, Oishi K, Rigoutsos I, Sano M, Sasaki A, Yasunori Sasakura, Shoguchi E, Shin-i T, Spagnuolo A, Stainier D, Suzuki MM, Tassy O, Takatori N, Tokuoka M, Yagi K, Yoshizaki F, Wada S, Zhang C, Hyatt PD, Larimer F, Detter C, Doggett N, Glavina T, Hawkins T, Richardson P  Lucas S, Kohara Y, Levine M, Satoh N, Rokhsar DS
The draft genome of Ciona intestinalis : insights into chordate and vertebrate origins.
Science (2002) 298:2157-2167.

Satou Y, Yamada L, Mochizuki Y, Takatori N, Kawashima T, Sasaki A, Hamaguchi M, Awazu S, Yagi K, Yasunori Sasakura, Nakayama A, Ishikawa H, Inaba K, Satoh N
A cDNA resource from the basal chordate Ciona intestinalis .
Genesis (2002) 33:153-154.


Yasunori Sasakura, Kazuhiro W. Makabe
Ascidian Wnt-5 gene is involved in the morphogenetic movement of notochord cells.
Development Growth and Differentiation. (2001) 43:573-582.

Yasunori Sasakura, Kazuhiro W. Makabe
A gene encoding a new ONECUT class homeodomain protein in the ascidian Halocynthia roretzi functions in the differentiation and specification of neural cells in ascidian embryogenesis.
Mechanisms of Development. (2001) 104:37-48 .

Satou Y, Takatori N, Yamada L, Mochizuki Y, Hamaguchi M, Ishikawa H, Chiba S, Imai K, Kano S, Murakami SD, Nakayama A, Nishino A, Yasunori Sasakura, Satoh G, Shimotori T, Shin-I T, Shoguchi E, Suzuki MM, Takada N, Utsumi N, Yoshida N, Saiga H, Kohara Y, Satoh N
Gene expression profiles in Ciona intestinalis tailbud embryos.
Development (2001) 128:2893-2904.

Makabe KW, Kawashima T, Kawashima S, Minokawa T, Adachi A, Kawamura H, Ishikawa H, Yasuda R, Yamamoto H, Kondoh K, Arioka S, Yasunori Sasakura, Kobayashi A, Yagi K, Shojima K, Kondoh Y, Kido S, Tsujinami M, Nishimura N, Takahashi M, Nakamura T, Kanehisa M, Ogasawara M, Nishikata T, Nishida H
Large-scale cDNA analysis of the maternal genetic information in the egg of Halocynthia roretzi for a gene expression catalog of ascidian development.
Development (2001) 128:2555-2567.

Kazuhiro W Makabe, Takeshi Kawashima, Shuichi Kawashima, Yasunori Sasakura , Hisayoshi Ishikawa, Hiroshi Kawamura, Minoru Kanehisa, Takahito Nishikata, Hiroki Nishida
Maternal genetic information stored in fertilized eggs of the ascidian, Halocynthia roretzi .
The Biology of Ascidians (2001) 159-165.


Yasunori Sasakura, Michio Ogasawara, Kazuhiro W. Makabe
Two pathways of maternal RNA localization at the posterior-vegetal cytoplasm in early ascidian embryos.
Developmental Biology. (2000) 220:365-78.

Yasunori Sasakura, Kazuhiro W. Makabe
Ascidian Wnt-7 gene is expressed exclusively in the tail neural tube of tailbud embryos.
Development Genes and Evolution. (2000) 210:641-643.

Michio Ogasawara, Minokawa T, Yasunori Sasakura, Hiroki Nishida, Kazuhiro W Makabe
A large-scale whole-mount in situ hybridization system: rapid one-tube preparation of DIG-labeled RNA probes and high throughput hybridization using 96-well silent screen plates.
Zoological Science (2000) 18:187-193.

Takeshi Kawashima, Akikazu R Murakami, Michio Ogasawara, Kimio J Tanaka, Ryuji Isoda, Yasunori Sasakura, Takahito Nishikata, Hideyuki Okano, Kazuhiro W Makabe
Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis .
Development Genes and Evolution. (2000) 210:162-165.


Ako Kobayashi, Yasunori Sasakura, Michio Ogasawara, Kazuhiro W Makabe
A maternal RNA encoding smad1/5 is segregated to animal blastomeres during ascidian development.
Development Growth and Differentiation. (1999) 41:419-427.


Yasunori Sasakura, Michio Ogasawara, Kazuhiro W. Makabe
Maternally localized RNA encoding a serine/threonine protein kinase in the ascidian, Halocynthia roretzi .
Mechanisms of Development. (1998) 76:161-163.

Yasunori Sasakura, Michio Ogasawara, Kazuhiro W. Makabe
HrWnt-5 : a maternally expressed ascidian Wnt gene with posterior localization in early embryos.
International Journal of Developmental Biology (1998) 42:573-579.

Copyright(c) 2008-2023 Sasakura Lab, All rights reserved.